Actin-binding LIM protein 2 (ABLIM2)
Homo sapiens — UniProt Q6H8Q1
Data last refreshed: (UniProt release unknown)
Key facts
Actin-binding LIM protein 2 (ABLIM2) is a protein from Homo sapiens identified by UniProt accession Q6H8Q1, 611 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q6H8Q1; gene symbol ABLIM2.
- Organism: Homo sapiens.
- Length: 611 amino acids.
- Top disease associations (Open Targets): triglyceride measurement, PHF-tau measurement and neurofibrillary tangles measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Actin-binding LIM protein 2 |
|---|---|
| UniProt accession | Q6H8Q1 |
| Gene | ABLIM2 |
| Organism | Homo sapiens |
| Length | 611 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- triglyceride measurement · score 0.36
- PHF-tau measurement · score 0.36
- neurofibrillary tangles measurement · score 0.29
- alcohol consumption measurement · score 0.26
- cutaneous melanoma · score 0.12
- Myopia · score 0.11
- pathological myopia · score 0.11
- metabolite measurement · score 0.05
- drug use measurement · score 0.04
- glioblastoma multiforme · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6H8Q1-F1 | alphafold | PREDICTED | 65.44 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6H8Q1.
Amino-acid sequence (611 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ABLIM2?
The strongest Open Targets associations for ABLIM2 are triglyceride measurement, PHF-tau measurement, neurofibrillary tangles measurement, alcohol consumption measurement and cutaneous melanoma.
How long is the ABLIM2 protein?
The Homo sapiens ABLIM2 protein (UniProt Q6H8Q1) is 611 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6H8Q1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6H8Q1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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