THO complex subunit 7 (THOC7)
Homo sapiens — UniProt Q6I9Y2
Data last refreshed: (UniProt release unknown)
Key facts
THO complex subunit 7 (THOC7) is a protein from Homo sapiens identified by UniProt accession Q6I9Y2, 204 residues long. MolForge cross-references it against 0 known binders and 89 disease associations.
- UniProt accession: Q6I9Y2; gene symbol THOC7.
- Organism: Homo sapiens.
- Length: 204 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, schizophrenia and neutrophil count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | THO complex subunit 7 |
|---|---|
| UniProt accession | Q6I9Y2 |
| Gene | THOC7 |
| Organism | Homo sapiens |
| Length | 204 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (89)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- schizophrenia · score 0.28
- neutrophil count · score 0.26
- leukocyte count · score 0.25
- cataract · score 0.24
- myeloid white cell count · score 0.24
- intelligence · score 0.16
- self reported educational attainment · score 0.16
- autism spectrum disorder · score 0.15
- unipolar depression · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6I9Y2-F1 | alphafold | PREDICTED | 87.69 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6I9Y2.
Amino-acid sequence (204 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with THOC7?
The strongest Open Targets associations for THOC7 are neurodegenerative disease, schizophrenia, neutrophil count, leukocyte count and cataract.
How long is the THOC7 protein?
The Homo sapiens THOC7 protein (UniProt Q6I9Y2) is 204 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6I9Y2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6I9Y2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.