Ragulator complex protein LAMTOR1 (LAMTOR1)
Homo sapiens — UniProt Q6IAA8
Data last refreshed: (UniProt release unknown)
Key facts
Ragulator complex protein LAMTOR1 (LAMTOR1) is a protein from Homo sapiens identified by UniProt accession Q6IAA8, 161 residues long. MolForge cross-references it against 0 known binders and 104 disease associations.
- UniProt accession: Q6IAA8; gene symbol LAMTOR1.
- Organism: Homo sapiens.
- Length: 161 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, deafness and autosomal recessive nonsyndromic hearing loss 63.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ragulator complex protein LAMTOR1 |
|---|---|
| UniProt accession | Q6IAA8 |
| Gene | LAMTOR1 |
| Organism | Homo sapiens |
| Length | 161 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (104)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- deafness · score 0.41
- autosomal recessive nonsyndromic hearing loss 63 · score 0.40
- Parkinson disease · score 0.34
- multiple sclerosis · score 0.34
- Alzheimer disease · score 0.34
- lysosomal storage disease · score 0.34
- Rare genetic deafness · score 0.27
- head and neck squamous cell carcinoma · score 0.18
- esophageal cancer · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6IAA8-F1 | alphafold | PREDICTED | 80.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6IAA8.
Amino-acid sequence (161 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LAMTOR1?
The strongest Open Targets associations for LAMTOR1 are neurodegenerative disease, deafness, autosomal recessive nonsyndromic hearing loss 63, Parkinson disease and multiple sclerosis.
How long is the LAMTOR1 protein?
The Homo sapiens LAMTOR1 protein (UniProt Q6IAA8) is 161 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6IAA8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6IAA8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.