Protein Jade-1 (JADE1)
Homo sapiens — UniProt Q6IE81
Data last refreshed: (UniProt release unknown)
Key facts
Protein Jade-1 (JADE1) is a protein from Homo sapiens identified by UniProt accession Q6IE81, 842 residues long. MolForge cross-references it against 0 known binders and 123 disease associations.
- UniProt accession: Q6IE81; gene symbol JADE1.
- Organism: Homo sapiens.
- Length: 842 amino acids.
- Top disease associations (Open Targets): mathematical ability, mean corpuscular volume and self reported educational attainment.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein Jade-1 |
|---|---|
| UniProt accession | Q6IE81 |
| Gene | JADE1 |
| Organism | Homo sapiens |
| Length | 842 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (123)
Diseases linked to this target (Open Targets).
- mathematical ability · score 0.45
- mean corpuscular volume · score 0.32
- self reported educational attainment · score 0.30
- body height · score 0.30
- mean reticulocyte volume · score 0.25
- sitting height measurement · score 0.24
- breast adenocarcinoma · score 0.22
- creatinine measurement · score 0.22
- cystatin C measurement · score 0.17
- risky sexual behaviour measurement · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6IE81-F1 | alphafold | PREDICTED | 61.66 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6IE81.
Amino-acid sequence (842 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with JADE1?
The strongest Open Targets associations for JADE1 are mathematical ability, mean corpuscular volume, self reported educational attainment, body height and mean reticulocyte volume.
How long is the JADE1 protein?
The Homo sapiens JADE1 protein (UniProt Q6IE81) is 842 amino acids long.
Browse: Targets: J · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6IE81 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6IE81 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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