U11/U12 small nuclear ribonucleoprotein 48 kDa protein (SNRNP48)
Homo sapiens — UniProt Q6IEG0
Data last refreshed: (UniProt release unknown)
Key facts
U11/U12 small nuclear ribonucleoprotein 48 kDa protein (SNRNP48) is a protein from Homo sapiens identified by UniProt accession Q6IEG0, 339 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q6IEG0; gene symbol SNRNP48.
- Organism: Homo sapiens.
- Length: 339 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, PHF-tau measurement and FEV/FVC ratio.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | U11/U12 small nuclear ribonucleoprotein 48 kDa protein |
|---|---|
| UniProt accession | Q6IEG0 |
| Gene | SNRNP48 |
| Organism | Homo sapiens |
| Length | 339 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- PHF-tau measurement · score 0.12
- FEV/FVC ratio · score 0.07
- interstitial lung disease · score 0.03
- vital capacity · score 0.03
- idiopathic pulmonary fibrosis · score 0.03
- chronic obstructive pulmonary disease · score 0.03
- advanced glycosylation end product-specific receptor ligand measurement · score 0.02
- Alzheimer disease · score 0.01
- neoplasm · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6IEG0-F1 | alphafold | PREDICTED | 71.58 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6IEG0.
Amino-acid sequence (339 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SNRNP48?
The strongest Open Targets associations for SNRNP48 are neurodegenerative disease, PHF-tau measurement, FEV/FVC ratio, interstitial lung disease and vital capacity.
How long is the SNRNP48 protein?
The Homo sapiens SNRNP48 protein (UniProt Q6IEG0) is 339 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6IEG0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6IEG0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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