Sulfotransferase 1C3 (SULT1C3)

About Sulfotransferase 1C3

Sulfotransferase 1C3 (SULT1C3) is a protein from Homo sapiens identified by UniProt accession Q6IMI6, 304 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein name	Sulfotransferase 1C3
UniProt accession	Q6IMI6
Gene	SULT1C3
Organism	Homo sapiens
Length	304 residues
Molecular weight	—
EC numbers	—
Target class	—
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (12)

Diseases linked to this target (Open Targets).

Agents acting on the renin-angiotensin system use measurement · score 0.23
malate measurement · score 0.08
hypouricemia, renal, 2 · score 0.03
hypermetabolism due to uncoupled mitochondrial oxidative phosphorylation 2 · score 0.03
lobe attachment · score 0.03
gut microbiome measurement · score 0.02
Colon Sessile Serrated Adenoma/Polyp · score 0.02
COVID-19 · score 0.01
Crohn's disease · score 0.00
psoriasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q6IMI6-F1	alphafold	PREDICTED	92.15	—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6IMI6.

Amino-acid sequence (304 residues)

MAKIEKNAPT MEKKPELFNI MEVDGVPTLI LSKEWWEKVC NFQAKPDDLI LATYPKSGTT WMHEILDMIL NDGDVEKCKR AQTLDRHAFL ELKFPHKEKP DLEFVLEMSS PQLIKTHLPS HLIPPSIWKE NCKIVYVARN PKDCLVSYYH FHRMASFMPD PQNLEEFYEK FMSGKVVGGS WFDHVKGWWA AKDMHRILYL FYEDIKKDPK REIEKILKFL EKDISEEILN KIIYHTSFDV MKQNPMTNYT TLPTSIMDHS ISPFMRKGMP GDWKNYFTVA QNEEFDKDYQ KKMAGSTLTF RTEI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards