Tyrosine-protein kinase STYK1 (STYK1)
Homo sapiens — UniProt Q6J9G0
Data last refreshed: (UniProt release unknown)
Key facts
Tyrosine-protein kinase STYK1 (STYK1) is a protein from Homo sapiens identified by UniProt accession Q6J9G0, 422 residues long. MolForge cross-references it against 0 known binders and 69 disease associations.
- UniProt accession: Q6J9G0; gene symbol STYK1.
- Organism: Homo sapiens.
- Length: 422 amino acids.
- Top disease associations (Open Targets): amyloid-beta measurement, non-small cell lung carcinoma and dentures.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Tyrosine-protein kinase STYK1 |
|---|---|
| UniProt accession | Q6J9G0 |
| Gene | STYK1 |
| Organism | Homo sapiens |
| Length | 422 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (69)
Diseases linked to this target (Open Targets).
- amyloid-beta measurement · score 0.19
- non-small cell lung carcinoma · score 0.11
- dentures · score 0.10
- neoplasm · score 0.08
- dental caries · score 0.08
- hepatocellular carcinoma · score 0.08
- urinary bladder carcinoma · score 0.07
- pancreatic neoplasm · score 0.07
- colorectal carcinoma · score 0.07
- chronic lymphocytic leukemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6J9G0-F1 | alphafold | PREDICTED | 83.65 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6J9G0.
Amino-acid sequence (422 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with STYK1?
The strongest Open Targets associations for STYK1 are amyloid-beta measurement, non-small cell lung carcinoma, dentures, neoplasm and dental caries.
How long is the STYK1 protein?
The Homo sapiens STYK1 protein (UniProt Q6J9G0) is 422 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6J9G0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6J9G0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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