Epididymal-specific lipocalin-10 (LCN10)
Homo sapiens — UniProt Q6JVE6
Data last refreshed: (UniProt release unknown)
Key facts
Epididymal-specific lipocalin-10 (LCN10) is a protein from Homo sapiens identified by UniProt accession Q6JVE6, 187 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.
- UniProt accession: Q6JVE6; gene symbol LCN10.
- Organism: Homo sapiens.
- Length: 187 amino acids.
- Top disease associations (Open Targets): uterine leiomyosarcoma, type 2 diabetes mellitus and appendicular lean mass.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Epididymal-specific lipocalin-10 |
|---|---|
| UniProt accession | Q6JVE6 |
| Gene | LCN10 |
| Organism | Homo sapiens |
| Length | 187 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (24)
Diseases linked to this target (Open Targets).
- uterine leiomyosarcoma · score 0.06
- type 2 diabetes mellitus · score 0.03
- appendicular lean mass · score 0.03
- Sepsis · score 0.03
- diabetes mellitus · score 0.02
- breast carcinoma · score 0.02
- Insulin resistance · score 0.02
- cervical squamous cell carcinoma · score 0.01
- Tetralogy of Fallot · score 0.01
- colorectal cancer · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6JVE6-F1 | alphafold | PREDICTED | 72.06 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6JVE6.
Amino-acid sequence (187 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LCN10?
The strongest Open Targets associations for LCN10 are uterine leiomyosarcoma, type 2 diabetes mellitus, appendicular lean mass, Sepsis and diabetes mellitus.
How long is the LCN10 protein?
The Homo sapiens LCN10 protein (UniProt Q6JVE6) is 187 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6JVE6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6JVE6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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