Keratin-associated protein 5-11 (KRTAP5-11)
Homo sapiens — UniProt Q6L8G4
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 5-11 (KRTAP5-11) is a protein from Homo sapiens identified by UniProt accession Q6L8G4, 156 residues long. MolForge cross-references it against 0 known binders and 7 disease associations.
- UniProt accession: Q6L8G4; gene symbol KRTAP5-11.
- Organism: Homo sapiens.
- Length: 156 amino acids.
- Top disease associations (Open Targets): osteoarthritis, glioblastoma multiforme and esophageal cancer.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 5-11 |
|---|---|
| UniProt accession | Q6L8G4 |
| Gene | KRTAP5-11 |
| Organism | Homo sapiens |
| Length | 156 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (7)
Diseases linked to this target (Open Targets).
- osteoarthritis · score 0.21
- glioblastoma multiforme · score 0.18
- esophageal cancer · score 0.14
- Hodgkins lymphoma · score 0.03
- adolescent idiopathic scoliosis · score 0.03
- gastric carcinoma · score 0.00
- diabetes mellitus · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6L8G4-F1 | alphafold | PREDICTED | 42.79 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6L8G4.
Amino-acid sequence (156 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP5-11?
The strongest Open Targets associations for KRTAP5-11 are osteoarthritis, glioblastoma multiforme, esophageal cancer, Hodgkins lymphoma and adolescent idiopathic scoliosis.
How long is the KRTAP5-11 protein?
The Homo sapiens KRTAP5-11 protein (UniProt Q6L8G4) is 156 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6L8G4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6L8G4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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