Keratin-associated protein 5-7 (KRTAP5-7)
Homo sapiens — UniProt Q6L8G8
Data last refreshed: (UniProt release unknown)
Key facts
Keratin-associated protein 5-7 (KRTAP5-7) is a protein from Homo sapiens identified by UniProt accession Q6L8G8, 165 residues long. MolForge cross-references it against 0 known binders and 10 disease associations.
- UniProt accession: Q6L8G8; gene symbol KRTAP5-7.
- Organism: Homo sapiens.
- Length: 165 amino acids.
- Top disease associations (Open Targets): vitamin D measurement, clear cell renal carcinoma and head and neck squamous cell carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Keratin-associated protein 5-7 |
|---|---|
| UniProt accession | Q6L8G8 |
| Gene | KRTAP5-7 |
| Organism | Homo sapiens |
| Length | 165 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (10)
Diseases linked to this target (Open Targets).
- vitamin D measurement · score 0.34
- clear cell renal carcinoma · score 0.18
- head and neck squamous cell carcinoma · score 0.18
- protein measurement · score 0.18
- multiple sclerosis · score 0.08
- Hodgkins lymphoma · score 0.03
- adolescent idiopathic scoliosis · score 0.03
- vitamin D deficiency · score 0.02
- vitamin D dietary intake measurement · score 0.02
- diabetes mellitus · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6L8G8-F1 | alphafold | PREDICTED | 42.29 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6L8G8.
Amino-acid sequence (165 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with KRTAP5-7?
The strongest Open Targets associations for KRTAP5-7 are vitamin D measurement, clear cell renal carcinoma, head and neck squamous cell carcinoma, protein measurement and multiple sclerosis.
How long is the KRTAP5-7 protein?
The Homo sapiens KRTAP5-7 protein (UniProt Q6L8G8) is 165 amino acids long.
Browse: Targets: K · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6L8G8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6L8G8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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