Protein FAM72D (FAM72D)
Homo sapiens — UniProt Q6L9T8
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM72D (FAM72D) is a protein from Homo sapiens identified by UniProt accession Q6L9T8, 149 residues long. MolForge cross-references it against 0 known binders and 66 disease associations.
- UniProt accession: Q6L9T8; gene symbol FAM72D.
- Organism: Homo sapiens.
- Length: 149 amino acids.
- Top disease associations (Open Targets): familial juvenile hyperuricemic nephropathy type 1, common variable immunodeficiency and combined immunodeficiency with skin granulomas.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM72D |
|---|---|
| UniProt accession | Q6L9T8 |
| Gene | FAM72D |
| Organism | Homo sapiens |
| Length | 149 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (66)
Diseases linked to this target (Open Targets).
- familial juvenile hyperuricemic nephropathy type 1 · score 0.06
- common variable immunodeficiency · score 0.05
- combined immunodeficiency with skin granulomas · score 0.05
- BENTA disease · score 0.05
- multicystic dysplastic kidney · score 0.05
- karyomegalic interstitial nephritis · score 0.04
- severe combined immunodeficiency due to CTPS1 deficiency · score 0.04
- immunodeficiency 18 · score 0.04
- xanthinuria type II · score 0.04
- hypoxanthine guanine phosphoribosyltransferase partial deficiency · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6L9T8-F1 | alphafold | PREDICTED | 84.74 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6L9T8.
Amino-acid sequence (149 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM72D?
The strongest Open Targets associations for FAM72D are familial juvenile hyperuricemic nephropathy type 1, common variable immunodeficiency, combined immunodeficiency with skin granulomas, BENTA disease and multicystic dysplastic kidney.
How long is the FAM72D protein?
The Homo sapiens FAM72D protein (UniProt Q6L9T8) is 149 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6L9T8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6L9T8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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