Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GALNT3)
Homo sapiens — UniProt Q6L9W6
Data last refreshed: (UniProt release unknown)
Key facts
Beta-1,4-N-acetylgalactosaminyltransferase 3 (B4GALNT3) is a protein from Homo sapiens identified by UniProt accession Q6L9W6, 998 residues long. MolForge cross-references it against 0 known binders and 54 disease associations.
- UniProt accession: Q6L9W6; gene symbol B4GALNT3.
- Organism: Homo sapiens.
- Length: 998 amino acids.
- Top disease associations (Open Targets): alkaline phosphatase measurement, body height and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Beta-1,4-N-acetylgalactosaminyltransferase 3 |
|---|---|
| UniProt accession | Q6L9W6 |
| Gene | B4GALNT3 |
| Organism | Homo sapiens |
| Length | 998 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (54)
Diseases linked to this target (Open Targets).
- alkaline phosphatase measurement · score 0.68
- body height · score 0.63
- heel bone mineral density · score 0.47
- sitting height measurement · score 0.46
- low density lipoprotein cholesterol measurement · score 0.46
- gut microbiome measurement · score 0.44
- bone quantitative ultrasound measurement · score 0.44
- blood protein measurement · score 0.43
- apolipoprotein B measurement · score 0.38
- total cholesterol measurement · score 0.38
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6L9W6-F1 | alphafold | PREDICTED | 71.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6L9W6.
Amino-acid sequence (998 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with B4GALNT3?
The strongest Open Targets associations for B4GALNT3 are alkaline phosphatase measurement, body height, heel bone mineral density, sitting height measurement and low density lipoprotein cholesterol measurement.
How long is the B4GALNT3 protein?
The Homo sapiens B4GALNT3 protein (UniProt Q6L9W6) is 998 amino acids long.
Browse: Targets: B · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6L9W6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6L9W6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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