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Regulator of G-protein signaling 7-binding protein (RGS7BP)

Homo sapiens — UniProt Q6MZT1

Gene: RGS7BPHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Regulator of G-protein signaling 7-binding protein (RGS7BP) is a protein from Homo sapiens identified by UniProt accession Q6MZT1, 257 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

  • UniProt accession: Q6MZT1; gene symbol RGS7BP.
  • Organism: Homo sapiens.
  • Length: 257 amino acids.
  • Top disease associations (Open Targets): chronotype measurement, mathematical ability and self reported educational attainment.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRegulator of G-protein signaling 7-binding protein
UniProt accessionQ6MZT1
GeneRGS7BP
OrganismHomo sapiens
Length257 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (32)

Diseases linked to this target (Open Targets).

  • chronotype measurement · score 0.46
  • mathematical ability · score 0.42
  • self reported educational attainment · score 0.38
  • systolic blood pressure · score 0.38
  • cardiovascular disease · score 0.29
  • blood pressure · score 0.18
  • hypertension · score 0.17
  • body mass index · score 0.10
  • body weight · score 0.08
  • body fat percentage · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6MZT1-F1alphafoldPREDICTED72.79—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6MZT1.

Amino-acid sequence (257 residues)

MSSAPNGRKK RPSRSTRSSI FQISKPPLQS GDWERRGSGS ESAHKTQRAL DDCKMLVQEF NTQVALYREL VISIGDVSVS CPSLRAEMHK TRTKGCEMAR QAHQKLAAIS GPEDGEIHPE ICRLYIQLQC CLEMYTTEML KSICLLGSLQ FHRKGKEPGG GTKSLDCKIE ESAETPALED SSSSPVDSQQ HSWQVSTDIE NTERDMREMK NLLSKLRETM PLPLKNQDDS SLLNLTPYPL VRRRKRRFFG LCCLISS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RGS7BP?

The strongest Open Targets associations for RGS7BP are chronotype measurement, mathematical ability, self reported educational attainment, systolic blood pressure and cardiovascular disease.

How long is the RGS7BP protein?

The Homo sapiens RGS7BP protein (UniProt Q6MZT1) is 257 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6MZT1
GeneRGS7BP
OrganismHomo sapiens
Length257
Binders0
Diseases32
View on UniProt