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RPA-related protein RADX (RADX)

Homo sapiens — UniProt Q6NSI4

Gene: RADXHomo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

RPA-related protein RADX (RADX) is a protein from Homo sapiens identified by UniProt accession Q6NSI4, 855 residues long. MolForge cross-references it against 0 known binders and 25 disease associations.

  • UniProt accession: Q6NSI4; gene symbol RADX.
  • Organism: Homo sapiens.
  • Length: 855 amino acids.
  • Top disease associations (Open Targets): ovarian carcinoma, breast carcinoma and endometrial carcinoma.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameRPA-related protein RADX
UniProt accessionQ6NSI4
GeneRADX
OrganismHomo sapiens
Length855 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (25)

Diseases linked to this target (Open Targets).

  • ovarian carcinoma · score 0.02
  • breast carcinoma · score 0.02
  • endometrial carcinoma · score 0.01
  • breast cancer · score 0.01
  • chronic myelogenous leukemia · score 0.01
  • chronic lymphocytic leukemia · score 0.01
  • chronic interstitial cystitis · score 0.01
  • neoplasm · score 0.01
  • Asperger syndrome · score 0.01
  • myeloproliferative disorder · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6NSI4-F1alphafoldPREDICTED75.44—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NSI4.

Amino-acid sequence (855 residues)

MSGESGQPEA GPSHAGLDWP NPERNRAGVP GGVIRRAGSQ GPRSWIQKVL EQIMDSPRQC VTPSEVVPVT VLAVQRYLLE DEPRDTVPKP PLYCYDVTIS DGVYQEKCYL DPSLNSLVYQ NILKVGIQMR ISRVSCLYNE KRIGQGILCI DNVHCGETSD SISLETPFRN RAHQEKPERP LRGGKSHYLA LWNNEDPYGD IWLTDKQPEE HNFSDTKIIS LSHLEMTWTN RRNFPALLVR ILHKSKLRYY GKPDKKMIEP YQTFLEVADS SGTVSVIMWN ALCPEWYKSL RVGLVLLLQD YSVKKSYPFR IQPVPVDPQI KLISTMEICL NLRDPPTNII IIPEKQVKPE WRLPKLNHRF TTRSELDDMP ENCICDVIGL LVFVGRVQRS KKKENREDFW SYRWIHIADG TSEQPFIVEL FSTSQPEIFE NIYPMAYFVC TQLKVVRNDN QVPKLLYLTT TNESGVFITG HRGQPYTYDA KVKNFIQWIR TKSDSGEQKN MVIGGYYPYP PVPETFSKYS SSIKVESLLT AISEVRKEIE DLQYREQKRI AIQGIITAIK YIPHSSATES ASASETLRNA NRPSTSQAAR VEIQERNGKR HQDDEPVNSQ YFQTTSTNLS LSNKIRILQG PHANPVAVPQ PGASVQTKGI KPGMPSIFNR RANINANLQG KARKTISDRW ESQLWREKKF GLIDHLHYSR VYPESIPRKF MFEHRKFLSD QYNSQPAKYV PPEGRPPKLD DFKSARSLGH FEVTILGLNH EIAIDVAFLP MYCPEDIRTS QIDTLLTSMN YSCAYPQDTT GNDRLPGPRA VAGDIIKAAT ELDRVHIVGI LDICNLGNNK VEVYLHKIYS PENTS

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with RADX?

The strongest Open Targets associations for RADX are ovarian carcinoma, breast carcinoma, endometrial carcinoma, breast cancer and chronic myelogenous leukemia.

How long is the RADX protein?

The Homo sapiens RADX protein (UniProt Q6NSI4) is 855 amino acids long.

Browse: Targets: R · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6NSI4
GeneRADX
OrganismHomo sapiens
Length855
Binders0
Diseases25
View on UniProt