Alpha-galactosidase MYORG (MYORG)
Homo sapiens — UniProt Q6NSJ0
Data last refreshed: (UniProt release unknown)
Key facts
Alpha-galactosidase MYORG (MYORG) is a protein from Homo sapiens identified by UniProt accession Q6NSJ0, 714 residues long. MolForge cross-references it against 0 known binders and 52 disease associations.
- UniProt accession: Q6NSJ0; gene symbol MYORG.
- Organism: Homo sapiens.
- Length: 714 amino acids.
- Top disease associations (Open Targets): bilateral striopallidodentate calcinosis, reticulocyte measurement and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Alpha-galactosidase MYORG |
|---|---|
| UniProt accession | Q6NSJ0 |
| Gene | MYORG |
| Organism | Homo sapiens |
| Length | 714 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (52)
Diseases linked to this target (Open Targets).
- bilateral striopallidodentate calcinosis · score 0.61
- reticulocyte measurement · score 0.24
- genetic disorder · score 0.15
- self reported educational attainment · score 0.14
- reticulocyte count · score 0.08
- Red cell distribution width · score 0.07
- diet measurement · score 0.07
- MODY · score 0.07
- 3-hydroxy-3-methylglutaryl-CoA synthase deficiency · score 0.05
- hyperproinsulinemia · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NSJ0-F1 | alphafold | PREDICTED | 90.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NSJ0.
Amino-acid sequence (714 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MYORG?
The strongest Open Targets associations for MYORG are bilateral striopallidodentate calcinosis, reticulocyte measurement, genetic disorder, self reported educational attainment and reticulocyte count.
How long is the MYORG protein?
The Homo sapiens MYORG protein (UniProt Q6NSJ0) is 714 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NSJ0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NSJ0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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