DNA dC->dU-editing enzyme APOBEC-3H (APOBEC3H)
Homo sapiens — UniProt Q6NTF7
Data last refreshed: (UniProt release unknown)
Key facts
DNA dC->dU-editing enzyme APOBEC-3H (APOBEC3H) is a protein from Homo sapiens identified by UniProt accession Q6NTF7, 200 residues long. MolForge cross-references it against 0 known binders and 95 disease associations.
- UniProt accession: Q6NTF7; gene symbol APOBEC3H.
- Organism: Homo sapiens.
- Length: 200 amino acids.
- Top disease associations (Open Targets): monocyte count, neurodegenerative disease and blood protein measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | DNA dC->dU-editing enzyme APOBEC-3H |
|---|---|
| UniProt accession | Q6NTF7 |
| Gene | APOBEC3H |
| Organism | Homo sapiens |
| Length | 200 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (95)
Diseases linked to this target (Open Targets).
- monocyte count · score 0.32
- neurodegenerative disease · score 0.29
- blood protein measurement · score 0.22
- myeloid white cell count · score 0.19
- multiple myeloma · score 0.19
- leukocyte count · score 0.18
- body height · score 0.16
- forced expiratory volume · score 0.15
- cutaneous melanoma · score 0.14
- platelet count · score 0.14
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NTF7-F1 | alphafold | PREDICTED | 89.21 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NTF7.
Amino-acid sequence (200 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with APOBEC3H?
The strongest Open Targets associations for APOBEC3H are monocyte count, neurodegenerative disease, blood protein measurement, myeloid white cell count and multiple myeloma.
How long is the APOBEC3H protein?
The Homo sapiens APOBEC3H protein (UniProt Q6NTF7) is 200 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NTF7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NTF7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.