Rhomboid domain-containing protein 2 (RHBDD2)
Homo sapiens — UniProt Q6NTF9
Data last refreshed: (UniProt release unknown)
Key facts
Rhomboid domain-containing protein 2 (RHBDD2) is a protein from Homo sapiens identified by UniProt accession Q6NTF9, 364 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q6NTF9; gene symbol RHBDD2.
- Organism: Homo sapiens.
- Length: 364 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, eosinophil count and eosinophil percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Rhomboid domain-containing protein 2 |
|---|---|
| UniProt accession | Q6NTF9 |
| Gene | RHBDD2 |
| Organism | Homo sapiens |
| Length | 364 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- eosinophil count · score 0.32
- eosinophil percentage of leukocytes · score 0.31
- neutrophil count · score 0.29
- CCL24 measurement · score 0.28
- blood protein measurement · score 0.27
- eosinophil percentage of granulocytes · score 0.24
- sum of eosinophil and basophil counts · score 0.22
- neutrophil percentage of granulocytes · score 0.22
- platelet crit · score 0.20
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NTF9-F1 | alphafold | PREDICTED | 67.82 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NTF9.
Amino-acid sequence (364 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RHBDD2?
The strongest Open Targets associations for RHBDD2 are neurodegenerative disease, eosinophil count, eosinophil percentage of leukocytes, neutrophil count and CCL24 measurement.
How long is the RHBDD2 protein?
The Homo sapiens RHBDD2 protein (UniProt Q6NTF9) is 364 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NTF9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NTF9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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