Proactivator polypeptide-like 1 (PSAPL1)
Homo sapiens — UniProt Q6NUJ1
Data last refreshed: (UniProt release unknown)
Key facts
Proactivator polypeptide-like 1 (PSAPL1) is a protein from Homo sapiens identified by UniProt accession Q6NUJ1, 521 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q6NUJ1; gene symbol PSAPL1.
- Organism: Homo sapiens.
- Length: 521 amino acids.
- Top disease associations (Open Targets): blood protein measurement, alcohol withdrawal and wrist fracture.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Proactivator polypeptide-like 1 |
|---|---|
| UniProt accession | Q6NUJ1 |
| Gene | PSAPL1 |
| Organism | Homo sapiens |
| Length | 521 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- blood protein measurement · score 0.41
- alcohol withdrawal · score 0.11
- wrist fracture · score 0.10
- atazanavir measurement · score 0.10
- adolescent idiopathic scoliosis · score 0.09
- PHF-tau measurement · score 0.09
- gut microbiome measurement · score 0.09
- risk-taking behaviour · score 0.04
- urate measurement · score 0.03
- heel bone mineral density · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NUJ1-F1 | alphafold | PREDICTED | 72.70 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NUJ1.
Amino-acid sequence (521 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PSAPL1?
The strongest Open Targets associations for PSAPL1 are blood protein measurement, alcohol withdrawal, wrist fracture, atazanavir measurement and adolescent idiopathic scoliosis.
How long is the PSAPL1 protein?
The Homo sapiens PSAPL1 protein (UniProt Q6NUJ1) is 521 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NUJ1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NUJ1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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