PWWP domain-containing protein 2B (PWWP2B)
Homo sapiens — UniProt Q6NUJ5
Data last refreshed: (UniProt release unknown)
Key facts
PWWP domain-containing protein 2B (PWWP2B) is a protein from Homo sapiens identified by UniProt accession Q6NUJ5, 590 residues long. MolForge cross-references it against 0 known binders and 31 disease associations.
- UniProt accession: Q6NUJ5; gene symbol PWWP2B.
- Organism: Homo sapiens.
- Length: 590 amino acids.
- Top disease associations (Open Targets): neuroticism measurement, body height and BMI-adjusted waist circumference.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PWWP domain-containing protein 2B |
|---|---|
| UniProt accession | Q6NUJ5 |
| Gene | PWWP2B |
| Organism | Homo sapiens |
| Length | 590 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (31)
Diseases linked to this target (Open Targets).
- neuroticism measurement · score 0.38
- body height · score 0.37
- BMI-adjusted waist circumference · score 0.27
- BMI-adjusted waist-hip ratio · score 0.26
- intracranial hemorrhage · score 0.24
- coffee consumption measurement · score 0.23
- age at first sexual intercourse measurement · score 0.22
- heel bone mineral density · score 0.21
- MODY · score 0.11
- eosinophil percentage of leukocytes · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NUJ5-F1 | alphafold | PREDICTED | 60.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NUJ5.
Amino-acid sequence (590 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PWWP2B?
The strongest Open Targets associations for PWWP2B are neuroticism measurement, body height, BMI-adjusted waist circumference, BMI-adjusted waist-hip ratio and intracranial hemorrhage.
How long is the PWWP2B protein?
The Homo sapiens PWWP2B protein (UniProt Q6NUJ5) is 590 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NUJ5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NUJ5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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