Acyl-coenzyme A synthetase ACSM5, mitochondrial (ACSM5)
Homo sapiens — UniProt Q6NUN0
Data last refreshed: (UniProt release unknown)
Key facts
Acyl-coenzyme A synthetase ACSM5, mitochondrial (ACSM5) is a protein from Homo sapiens identified by UniProt accession Q6NUN0, 579 residues long. MolForge cross-references it against 0 known binders and 71 disease associations.
- UniProt accession: Q6NUN0; gene symbol ACSM5.
- Organism: Homo sapiens.
- Length: 579 amino acids.
- Top disease associations (Open Targets): protein measurement, cutaneous melanoma and lung adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Acyl-coenzyme A synthetase ACSM5, mitochondrial |
|---|---|
| UniProt accession | Q6NUN0 |
| Gene | ACSM5 |
| Organism | Homo sapiens |
| Length | 579 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (71)
Diseases linked to this target (Open Targets).
- protein measurement · score 0.32
- cutaneous melanoma · score 0.25
- lung adenocarcinoma · score 0.25
- glioblastoma multiforme · score 0.16
- squamous cell lung carcinoma · score 0.15
- head and neck squamous cell carcinoma · score 0.15
- fat body mass · score 0.13
- glomerular filtration rate · score 0.10
- chronic kidney disease · score 0.10
- blood urea nitrogen measurement · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NUN0-F1 | alphafold | PREDICTED | 90.35 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NUN0.
Amino-acid sequence (579 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ACSM5?
The strongest Open Targets associations for ACSM5 are protein measurement, cutaneous melanoma, lung adenocarcinoma, glioblastoma multiforme and squamous cell lung carcinoma.
How long is the ACSM5 protein?
The Homo sapiens ACSM5 protein (UniProt Q6NUN0) is 579 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NUN0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NUN0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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