Zinc finger protein 746 (ZNF746)
Homo sapiens — UniProt Q6NUN9
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 746 (ZNF746) is a protein from Homo sapiens identified by UniProt accession Q6NUN9, 644 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.
- UniProt accession: Q6NUN9; gene symbol ZNF746.
- Organism: Homo sapiens.
- Length: 644 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, reticulocyte count and reticulocyte measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 746 |
|---|---|
| UniProt accession | Q6NUN9 |
| Gene | ZNF746 |
| Organism | Homo sapiens |
| Length | 644 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (45)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.44
- reticulocyte count · score 0.33
- reticulocyte measurement · score 0.30
- brain aneurysm · score 0.30
- multiple sclerosis · score 0.29
- Immature Reticulocyte Fraction Measurement · score 0.28
- mean corpuscular volume · score 0.28
- mean corpuscular hemoglobin concentration · score 0.26
- amyotrophic lateral sclerosis · score 0.25
- type 2 diabetes mellitus · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NUN9-F1 | alphafold | PREDICTED | 51.28 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NUN9.
Amino-acid sequence (644 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF746?
The strongest Open Targets associations for ZNF746 are neurodegenerative disease, reticulocyte count, reticulocyte measurement, brain aneurysm and multiple sclerosis.
How long is the ZNF746 protein?
The Homo sapiens ZNF746 protein (UniProt Q6NUN9) is 644 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NUN9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NUN9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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