UDP-glucuronosyltransferase 3A1 (UGT3A1)
Homo sapiens — UniProt Q6NUS8
Data last refreshed: (UniProt release unknown)
Key facts
UDP-glucuronosyltransferase 3A1 (UGT3A1) is a protein from Homo sapiens identified by UniProt accession Q6NUS8, 523 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.
- UniProt accession: Q6NUS8; gene symbol UGT3A1.
- Organism: Homo sapiens.
- Length: 523 amino acids.
- Top disease associations (Open Targets): serum metabolite measurement, urinary metabolite measurement and estradiol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | UDP-glucuronosyltransferase 3A1 |
|---|---|
| UniProt accession | Q6NUS8 |
| Gene | UGT3A1 |
| Organism | Homo sapiens |
| Length | 523 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (38)
Diseases linked to this target (Open Targets).
- serum metabolite measurement · score 0.47
- urinary metabolite measurement · score 0.41
- estradiol measurement · score 0.39
- blood metabolite measurement · score 0.33
- serum non-albumin protein measurement · score 0.25
- eosinophil percentage of leukocytes · score 0.23
- asthma · score 0.19
- cutaneous melanoma · score 0.18
- lung adenocarcinoma · score 0.17
- glioblastoma multiforme · score 0.17
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NUS8-F1 | alphafold | PREDICTED | 91.42 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NUS8.
Amino-acid sequence (523 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with UGT3A1?
The strongest Open Targets associations for UGT3A1 are serum metabolite measurement, urinary metabolite measurement, estradiol measurement, blood metabolite measurement and serum non-albumin protein measurement.
How long is the UGT3A1 protein?
The Homo sapiens UGT3A1 protein (UniProt Q6NUS8) is 523 amino acids long.
Browse: Targets: U · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NUS8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NUS8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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