CRACD-like protein (CRACDL)
Homo sapiens — UniProt Q6NV74
Data last refreshed: (UniProt release unknown)
Key facts
CRACD-like protein (CRACDL) is a protein from Homo sapiens identified by UniProt accession Q6NV74, 962 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q6NV74; gene symbol CRACDL.
- Organism: Homo sapiens.
- Length: 962 amino acids.
- Top disease associations (Open Targets): eosinophil count, plasma fibronectin deficiency and Combined hyperlipidemia.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | CRACD-like protein |
|---|---|
| UniProt accession | Q6NV74 |
| Gene | CRACDL |
| Organism | Homo sapiens |
| Length | 962 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.08
- plasma fibronectin deficiency · score 0.05
- Combined hyperlipidemia · score 0.05
- cholesterol-ester transfer protein deficiency · score 0.05
- hypertriglyceridemia 2 · score 0.05
- pseudohypoparathyroidism type 2 · score 0.04
- hypoparathyroidism, familial isolated, 2 · score 0.04
- Familial isolated hypoparathyroidism · score 0.04
- hemochromatosis type 5 · score 0.04
- FTH1-related iron overload · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NV74-F1 | alphafold | PREDICTED | 49.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NV74.
Amino-acid sequence (962 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CRACDL?
The strongest Open Targets associations for CRACDL are eosinophil count, plasma fibronectin deficiency, Combined hyperlipidemia, cholesterol-ester transfer protein deficiency and hypertriglyceridemia 2.
How long is the CRACDL protein?
The Homo sapiens CRACDL protein (UniProt Q6NV74) is 962 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NV74 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NV74 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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