ATPase SWSAP1 (SWSAP1)
Homo sapiens — UniProt Q6NVH7
Data last refreshed: (UniProt release unknown)
Key facts
ATPase SWSAP1 (SWSAP1) is a protein from Homo sapiens identified by UniProt accession Q6NVH7, 229 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.
- UniProt accession: Q6NVH7; gene symbol SWSAP1.
- Organism: Homo sapiens.
- Length: 229 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, azoospermia and partial chromosome Y deletion.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | ATPase SWSAP1 |
|---|---|
| UniProt accession | Q6NVH7 |
| Gene | SWSAP1 |
| Organism | Homo sapiens |
| Length | 229 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (131)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.17
- azoospermia · score 0.08
- partial chromosome Y deletion · score 0.07
- male infertility with teratozoospermia due to single gene mutation · score 0.07
- primary ovarian insufficiency · score 0.06
- isolated congenital hypogonadotropic hypogonadism · score 0.06
- platelet count · score 0.06
- spermatogenic failure, X-linked, 2 · score 0.06
- Testicular regression syndrome · score 0.06
- 46,XX testicular disorder of sex development · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NVH7-F1 | alphafold | PREDICTED | 81.99 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NVH7.
Amino-acid sequence (229 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SWSAP1?
The strongest Open Targets associations for SWSAP1 are neurodegenerative disease, azoospermia, partial chromosome Y deletion, male infertility with teratozoospermia due to single gene mutation and primary ovarian insufficiency.
How long is the SWSAP1 protein?
The Homo sapiens SWSAP1 protein (UniProt Q6NVH7) is 229 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NVH7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NVH7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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