Zinc finger protein 774 (ZNF774)
Homo sapiens — UniProt Q6NX45
Data last refreshed: (UniProt release unknown)
Key facts
Zinc finger protein 774 (ZNF774) is a protein from Homo sapiens identified by UniProt accession Q6NX45, 483 residues long. MolForge cross-references it against 0 known binders and 26 disease associations.
- UniProt accession: Q6NX45; gene symbol ZNF774.
- Organism: Homo sapiens.
- Length: 483 amino acids.
- Top disease associations (Open Targets): leukocyte count, allergic disease and allergic rhinitis.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc finger protein 774 |
|---|---|
| UniProt accession | Q6NX45 |
| Gene | ZNF774 |
| Organism | Homo sapiens |
| Length | 483 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (26)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.16
- allergic disease · score 0.14
- allergic rhinitis · score 0.12
- age at onset · score 0.11
- neutrophil percentage of leukocytes · score 0.08
- multiple sclerosis · score 0.07
- lymphocyte percentage of leukocytes · score 0.07
- birth weight · score 0.04
- parental genotype effect measurement · score 0.04
- heel bone mineral density · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NX45-F1 | alphafold | PREDICTED | 72.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NX45.
Amino-acid sequence (483 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ZNF774?
The strongest Open Targets associations for ZNF774 are leukocyte count, allergic disease, allergic rhinitis, age at onset and neutrophil percentage of leukocytes.
How long is the ZNF774 protein?
The Homo sapiens ZNF774 protein (UniProt Q6NX45) is 483 amino acids long.
Browse: Targets: Z · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NX45 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NX45 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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