Armadillo repeat-containing protein 6 (ARMC6)
Homo sapiens — UniProt Q6NXE6
Data last refreshed: (UniProt release unknown)
Key facts
Armadillo repeat-containing protein 6 (ARMC6) is a protein from Homo sapiens identified by UniProt accession Q6NXE6, 501 residues long. MolForge cross-references it against 0 known binders and 9 disease associations.
- UniProt accession: Q6NXE6; gene symbol ARMC6.
- Organism: Homo sapiens.
- Length: 501 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, DNA methylation and neuroblastoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Armadillo repeat-containing protein 6 |
|---|---|
| UniProt accession | Q6NXE6 |
| Gene | ARMC6 |
| Organism | Homo sapiens |
| Length | 501 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.32
- DNA methylation · score 0.04
- neuroblastoma · score 0.03
- diffuse large B-cell lymphoma · score 0.02
- cancer · score 0.01
- thanatophoric dysplasia · score 0.01
- schizophrenia · score 0.00
- nervous system disease · score 0.00
- acute myeloid leukemia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NXE6-F1 | alphafold | PREDICTED | 90.92 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NXE6.
Amino-acid sequence (501 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with ARMC6?
The strongest Open Targets associations for ARMC6 are neurodegenerative disease, DNA methylation, neuroblastoma, diffuse large B-cell lymphoma and cancer.
How long is the ARMC6 protein?
The Homo sapiens ARMC6 protein (UniProt Q6NXE6) is 501 amino acids long.
Browse: Targets: A · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NXE6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NXE6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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