NADP-dependent oxidoreductase domain-containing protein 1 (NOXRED1)
Homo sapiens — UniProt Q6NXP6
Data last refreshed: (UniProt release unknown)
Key facts
NADP-dependent oxidoreductase domain-containing protein 1 (NOXRED1) is a protein from Homo sapiens identified by UniProt accession Q6NXP6, 359 residues long. MolForge cross-references it against 0 known binders and 15 disease associations.
- UniProt accession: Q6NXP6; gene symbol NOXRED1.
- Organism: Homo sapiens.
- Length: 359 amino acids.
- Top disease associations (Open Targets): neutrophil count, eosinophil count and functional brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NADP-dependent oxidoreductase domain-containing protein 1 |
|---|---|
| UniProt accession | Q6NXP6 |
| Gene | NOXRED1 |
| Organism | Homo sapiens |
| Length | 359 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (15)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.12
- eosinophil count · score 0.12
- functional brain measurement · score 0.12
- white matter microstructure measurement · score 0.12
- leukocyte count · score 0.10
- myeloid white cell count · score 0.10
- apolipoprotein A 1 measurement · score 0.10
- granulocyte count · score 0.09
- sum of neutrophil and eosinophil counts · score 0.07
- protein measurement · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NXP6-F1 | alphafold | PREDICTED | 86.68 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NXP6.
Amino-acid sequence (359 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NOXRED1?
The strongest Open Targets associations for NOXRED1 are neutrophil count, eosinophil count, functional brain measurement, white matter microstructure measurement and leukocyte count.
How long is the NOXRED1 protein?
The Homo sapiens NOXRED1 protein (UniProt Q6NXP6) is 359 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NXP6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NXP6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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