Protein phosphatase inhibitor 2 family member B (PPP1R2B)
Homo sapiens — UniProt Q6NXS1
Data last refreshed: (UniProt release unknown)
Key facts
Protein phosphatase inhibitor 2 family member B (PPP1R2B) is a protein from Homo sapiens identified by UniProt accession Q6NXS1, 205 residues long. MolForge cross-references it against 0 known binders and 16 disease associations.
- UniProt accession: Q6NXS1; gene symbol PPP1R2B.
- Organism: Homo sapiens.
- Length: 205 amino acids.
- Top disease associations (Open Targets): lymphocyte count, pulse pressure measurement and alcohol consumption measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein phosphatase inhibitor 2 family member B |
|---|---|
| UniProt accession | Q6NXS1 |
| Gene | PPP1R2B |
| Organism | Homo sapiens |
| Length | 205 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (16)
Diseases linked to this target (Open Targets).
- lymphocyte count · score 0.12
- pulse pressure measurement · score 0.08
- alcohol consumption measurement · score 0.07
- attention deficit hyperactivity disorder · score 0.06
- hepatitis A virus cellular receptor 1 measurement · score 0.05
- response to bronchodilator · score 0.05
- FEV change measurement · score 0.05
- T-cell immunoglobulin and mucin domain 1 measurement · score 0.04
- testosterone measurement · score 0.03
- schizophrenia symptom severity measurement · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NXS1-F1 | alphafold | PREDICTED | 67.78 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NXS1.
Amino-acid sequence (205 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PPP1R2B?
The strongest Open Targets associations for PPP1R2B are lymphocyte count, pulse pressure measurement, alcohol consumption measurement, attention deficit hyperactivity disorder and hepatitis A virus cellular receptor 1 measurement.
How long is the PPP1R2B protein?
The Homo sapiens PPP1R2B protein (UniProt Q6NXS1) is 205 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NXS1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NXS1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.