Zinc transporter 6 (SLC30A6)
Homo sapiens — UniProt Q6NXT4
Data last refreshed: (UniProt release unknown)
Key facts
Zinc transporter 6 (SLC30A6) is a protein from Homo sapiens identified by UniProt accession Q6NXT4, 461 residues long. MolForge cross-references it against 0 known binders and 65 disease associations.
- UniProt accession: Q6NXT4; gene symbol SLC30A6.
- Organism: Homo sapiens.
- Length: 461 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): Autosomal dominant spastic paraplegia type 4, hereditary spastic paraplegia 4 and interleukin 18 measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Zinc transporter 6 |
|---|---|
| UniProt accession | Q6NXT4 |
| Gene | SLC30A6 |
| Organism | Homo sapiens |
| Length | 461 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (65)
Diseases linked to this target (Open Targets).
- Autosomal dominant spastic paraplegia type 4 · score 0.53
- hereditary spastic paraplegia 4 · score 0.53
- interleukin 18 measurement · score 0.12
- acute myeloid leukemia · score 0.11
- glucuronate measurement · score 0.09
- blood protein measurement · score 0.08
- Fuchs endothelial corneal dystrophy · score 0.07
- Lisch epithelial corneal dystrophy · score 0.07
- lymphocyte count · score 0.06
- keratoconus 1 · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NXT4-F1 | alphafold | PREDICTED | 71.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NXT4.
Amino-acid sequence (461 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC30A6?
The strongest Open Targets associations for SLC30A6 are Autosomal dominant spastic paraplegia type 4, hereditary spastic paraplegia 4, interleukin 18 measurement, acute myeloid leukemia and glucuronate measurement.
How long is the SLC30A6 protein?
The Homo sapiens SLC30A6 protein (UniProt Q6NXT4) is 461 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NXT4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NXT4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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