Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (JMJD6)
Homo sapiens — UniProt Q6NYC1
Data last refreshed: (UniProt release unknown)
Key facts
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 (JMJD6) is a protein from Homo sapiens identified by UniProt accession Q6NYC1, 403 residues long. MolForge cross-references it against 0 known binders and 178 disease associations.
- UniProt accession: Q6NYC1; gene symbol JMJD6.
- Organism: Homo sapiens.
- Length: 403 amino acids.
- Top disease associations (Open Targets): neutrophil count, alkaline phosphatase measurement and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6 |
|---|---|
| UniProt accession | Q6NYC1 |
| Gene | JMJD6 |
| Organism | Homo sapiens |
| Length | 403 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (178)
Diseases linked to this target (Open Targets).
- neutrophil count · score 0.28
- alkaline phosphatase measurement · score 0.25
- breast adenocarcinoma · score 0.22
- mathematical ability · score 0.18
- leukocyte count · score 0.12
- neoplasm · score 0.11
- cancer · score 0.10
- melanoma · score 0.10
- neuroblastoma · score 0.09
- chronic hepatitis B virus infection · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NYC1-F1 | alphafold | PREDICTED | 87.32 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NYC1.
Amino-acid sequence (403 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with JMJD6?
The strongest Open Targets associations for JMJD6 are neutrophil count, alkaline phosphatase measurement, breast adenocarcinoma, mathematical ability and leukocyte count.
How long is the JMJD6 protein?
The Homo sapiens JMJD6 protein (UniProt Q6NYC1) is 403 amino acids long.
Browse: Targets: J · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NYC1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NYC1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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