Caveolae-associated protein 1 (CAVIN1)
Homo sapiens — UniProt Q6NZI2
Data last refreshed: (UniProt release unknown)
Key facts
Caveolae-associated protein 1 (CAVIN1) is a protein from Homo sapiens identified by UniProt accession Q6NZI2, 390 residues long. MolForge cross-references it against 0 known binders and 184 disease associations.
- UniProt accession: Q6NZI2; gene symbol CAVIN1.
- Organism: Homo sapiens.
- Length: 390 amino acids.
- Top disease associations (Open Targets): congenital generalized lipodystrophy type 4, Generalized congenital lipodystrophy with myopathy and congenital generalized lipodystrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Caveolae-associated protein 1 |
|---|---|
| UniProt accession | Q6NZI2 |
| Gene | CAVIN1 |
| Organism | Homo sapiens |
| Length | 390 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (184)
Diseases linked to this target (Open Targets).
- congenital generalized lipodystrophy type 4 · score 0.63
- Generalized congenital lipodystrophy with myopathy · score 0.62
- congenital generalized lipodystrophy · score 0.46
- mean platelet volume · score 0.27
- Crohn's disease · score 0.22
- monocyte count · score 0.22
- seasonal allergic rhinitis · score 0.18
- monogenic diabetes · score 0.17
- asthma · score 0.14
- BMI-adjusted hip circumference · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NZI2-F1 | alphafold | PREDICTED | 67.40 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NZI2.
Amino-acid sequence (390 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CAVIN1?
The strongest Open Targets associations for CAVIN1 are congenital generalized lipodystrophy type 4, Generalized congenital lipodystrophy with myopathy, congenital generalized lipodystrophy, mean platelet volume and Crohn's disease.
How long is the CAVIN1 protein?
The Homo sapiens CAVIN1 protein (UniProt Q6NZI2) is 390 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NZI2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NZI2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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