Cdc42 effector protein 5 (CDC42EP5)
Homo sapiens — UniProt Q6NZY7
Data last refreshed: (UniProt release unknown)
Key facts
Cdc42 effector protein 5 (CDC42EP5) is a protein from Homo sapiens identified by UniProt accession Q6NZY7, 148 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.
- UniProt accession: Q6NZY7; gene symbol CDC42EP5.
- Organism: Homo sapiens.
- Length: 148 amino acids.
- Top disease associations (Open Targets): Parkinson disease, multiple sclerosis and lysosomal storage disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Cdc42 effector protein 5 |
|---|---|
| UniProt accession | Q6NZY7 |
| Gene | CDC42EP5 |
| Organism | Homo sapiens |
| Length | 148 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (44)
Diseases linked to this target (Open Targets).
- Parkinson disease · score 0.33
- multiple sclerosis · score 0.33
- lysosomal storage disease · score 0.33
- Alzheimer disease · score 0.33
- neurodegenerative disease · score 0.33
- self reported educational attainment · score 0.10
- melanoma · score 0.08
- linear and whorled nevoid hypermelanosis · score 0.05
- Red cell distribution width · score 0.04
- uncombable hair syndrome · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6NZY7-F1 | alphafold | PREDICTED | 64.75 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6NZY7.
Amino-acid sequence (148 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CDC42EP5?
The strongest Open Targets associations for CDC42EP5 are Parkinson disease, multiple sclerosis, lysosomal storage disease, Alzheimer disease and neurodegenerative disease.
How long is the CDC42EP5 protein?
The Homo sapiens CDC42EP5 protein (UniProt Q6NZY7) is 148 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6NZY7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6NZY7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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