Protein FAM180B (FAM180B)
Homo sapiens — UniProt Q6P0A1
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM180B (FAM180B) is a protein from Homo sapiens identified by UniProt accession Q6P0A1, 183 residues long. MolForge cross-references it against 0 known binders and 62 disease associations.
- UniProt accession: Q6P0A1; gene symbol FAM180B.
- Organism: Homo sapiens.
- Length: 183 amino acids.
- Top disease associations (Open Targets): body fat percentage, body mass index and high density lipoprotein cholesterol measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM180B |
|---|---|
| UniProt accession | Q6P0A1 |
| Gene | FAM180B |
| Organism | Homo sapiens |
| Length | 183 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (62)
Diseases linked to this target (Open Targets).
- body fat percentage · score 0.18
- body mass index · score 0.17
- high density lipoprotein cholesterol measurement · score 0.17
- lean body mass · score 0.16
- platelet count · score 0.16
- fat body mass · score 0.15
- aspartate aminotransferase measurement · score 0.14
- sex hormone-binding globulin measurement · score 0.12
- serum alanine aminotransferase measurement · score 0.12
- low density lipoprotein triglyceride measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P0A1-F1 | alphafold | PREDICTED | 77.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P0A1.
Amino-acid sequence (183 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM180B?
The strongest Open Targets associations for FAM180B are body fat percentage, body mass index, high density lipoprotein cholesterol measurement, lean body mass and platelet count.
How long is the FAM180B protein?
The Homo sapiens FAM180B protein (UniProt Q6P0A1) is 183 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P0A1 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P0A1 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.