Mis18-binding protein 1 (MIS18BP1)
Homo sapiens — UniProt Q6P0N0
Data last refreshed: (UniProt release unknown)
Key facts
Mis18-binding protein 1 (MIS18BP1) is a protein from Homo sapiens identified by UniProt accession Q6P0N0, 1132 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.
- UniProt accession: Q6P0N0; gene symbol MIS18BP1.
- Organism: Homo sapiens.
- Length: 1132 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, self reported educational attainment and age at menopause.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Mis18-binding protein 1 |
|---|---|
| UniProt accession | Q6P0N0 |
| Gene | MIS18BP1 |
| Organism | Homo sapiens |
| Length | 1132 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (21)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.51
- self reported educational attainment · score 0.20
- age at menopause · score 0.12
- metabolite measurement · score 0.11
- DNA methylation · score 0.06
- sphingomyelin measurement · score 0.05
- influenza A (H1N1) · score 0.02
- colorectal cancer · score 0.01
- psoriasis · score 0.01
- IGA glomerulonephritis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P0N0-F1 | alphafold | PREDICTED | 48.30 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P0N0.
Amino-acid sequence (1132 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MIS18BP1?
The strongest Open Targets associations for MIS18BP1 are neurodegenerative disease, self reported educational attainment, age at menopause, metabolite measurement and DNA methylation.
How long is the MIS18BP1 protein?
The Homo sapiens MIS18BP1 protein (UniProt Q6P0N0) is 1132 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P0N0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P0N0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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