Lysophospholipid acyltransferase 5 (LPCAT3)
Homo sapiens — UniProt Q6P1A2
Data last refreshed: (UniProt release unknown)
Key facts
Lysophospholipid acyltransferase 5 (LPCAT3) is a protein from Homo sapiens identified by UniProt accession Q6P1A2, 487 residues long. MolForge cross-references it against 0 known binders and 141 disease associations.
- UniProt accession: Q6P1A2; gene symbol LPCAT3.
- Organism: Homo sapiens.
- Length: 487 amino acids.
- Top disease associations (Open Targets): eosinophil count, Red cell distribution width and breast adenocarcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Lysophospholipid acyltransferase 5 |
|---|---|
| UniProt accession | Q6P1A2 |
| Gene | LPCAT3 |
| Organism | Homo sapiens |
| Length | 487 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (141)
Diseases linked to this target (Open Targets).
- eosinophil count · score 0.24
- Red cell distribution width · score 0.18
- breast adenocarcinoma · score 0.18
- mean corpuscular hemoglobin concentration · score 0.18
- mean reticulocyte volume · score 0.16
- mean corpuscular volume · score 0.16
- hemoglobin A1 measurement · score 0.15
- oleic acid measurement · score 0.15
- eosinophil percentage of leukocytes · score 0.14
- reticulocyte count · score 0.13
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P1A2-F1 | alphafold | PREDICTED | 92.04 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P1A2.
Amino-acid sequence (487 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LPCAT3?
The strongest Open Targets associations for LPCAT3 are eosinophil count, Red cell distribution width, breast adenocarcinoma, mean corpuscular hemoglobin concentration and mean reticulocyte volume.
How long is the LPCAT3 protein?
The Homo sapiens LPCAT3 protein (UniProt Q6P1A2) is 487 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P1A2 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P1A2 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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