Protein FAM117B (FAM117B)
Homo sapiens — UniProt Q6P1L5
Data last refreshed: (UniProt release unknown)
Key facts
Protein FAM117B (FAM117B) is a protein from Homo sapiens identified by UniProt accession Q6P1L5, 589 residues long. MolForge cross-references it against 0 known binders and 40 disease associations.
- UniProt accession: Q6P1L5; gene symbol FAM117B.
- Organism: Homo sapiens.
- Length: 589 amino acids.
- Top disease associations (Open Targets): low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement and reticulocyte count.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Protein FAM117B |
|---|---|
| UniProt accession | Q6P1L5 |
| Gene | FAM117B |
| Organism | Homo sapiens |
| Length | 589 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (40)
Diseases linked to this target (Open Targets).
- low density lipoprotein cholesterol measurement · score 0.46
- high density lipoprotein cholesterol measurement · score 0.43
- reticulocyte count · score 0.42
- total cholesterol measurement · score 0.42
- blood protein measurement · score 0.38
- apolipoprotein A 1 measurement · score 0.38
- apolipoprotein B measurement · score 0.37
- neurodegenerative disease · score 0.37
- sarcoidosis · score 0.36
- brain measurement · score 0.29
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P1L5-F1 | alphafold | PREDICTED | 52.60 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P1L5.
Amino-acid sequence (589 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAM117B?
The strongest Open Targets associations for FAM117B are low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement, reticulocyte count, total cholesterol measurement and blood protein measurement.
How long is the FAM117B protein?
The Homo sapiens FAM117B protein (UniProt Q6P1L5) is 589 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P1L5 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P1L5 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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