Large ribosomal subunit protein uL14m (MRPL14)
Homo sapiens — UniProt Q6P1L8
Data last refreshed: (UniProt release unknown)
Key facts
Large ribosomal subunit protein uL14m (MRPL14) is a protein from Homo sapiens identified by UniProt accession Q6P1L8, 145 residues long. MolForge cross-references it against 0 known binders and 50 disease associations.
- UniProt accession: Q6P1L8; gene symbol MRPL14.
- Organism: Homo sapiens.
- Length: 145 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, mean platelet volume and serum albumin measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Large ribosomal subunit protein uL14m |
|---|---|
| UniProt accession | Q6P1L8 |
| Gene | MRPL14 |
| Organism | Homo sapiens |
| Length | 145 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (50)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- mean platelet volume · score 0.25
- serum albumin measurement · score 0.17
- erythrocyte count · score 0.17
- hemoglobin measurement · score 0.16
- vascular endothelial growth factor measurement · score 0.16
- interleukin 12 measurement · score 0.13
- calcium measurement · score 0.13
- total blood protein measurement · score 0.12
- interleukin 10 measurement · score 0.12
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P1L8-F1 | alphafold | PREDICTED | 85.47 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P1L8.
Amino-acid sequence (145 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with MRPL14?
The strongest Open Targets associations for MRPL14 are neurodegenerative disease, mean platelet volume, serum albumin measurement, erythrocyte count and hemoglobin measurement.
How long is the MRPL14 protein?
The Homo sapiens MRPL14 protein (UniProt Q6P1L8) is 145 amino acids long.
Browse: Targets: M · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P1L8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P1L8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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