Long-chain fatty acid transport protein 4 (SLC27A4)
Homo sapiens — UniProt Q6P1M0
Data last refreshed: (UniProt release unknown)
Key facts
Long-chain fatty acid transport protein 4 (SLC27A4) is a protein from Homo sapiens identified by UniProt accession Q6P1M0, 643 residues long. MolForge cross-references it against 0 known binders and 179 disease associations.
- UniProt accession: Q6P1M0; gene symbol SLC27A4.
- Organism: Homo sapiens.
- Length: 643 amino acids.
- Top disease associations (Open Targets): ichthyosis prematurity syndrome, neurodegenerative disease and genetic disorder.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Long-chain fatty acid transport protein 4 |
|---|---|
| UniProt accession | Q6P1M0 |
| Gene | SLC27A4 |
| Organism | Homo sapiens |
| Length | 643 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (179)
Diseases linked to this target (Open Targets).
- ichthyosis prematurity syndrome · score 0.80
- neurodegenerative disease · score 0.48
- genetic disorder · score 0.47
- lamellar ichthyosis · score 0.39
- autosomal recessive disease · score 0.37
- cutaneous melanoma · score 0.15
- neoplasm · score 0.09
- focal palmoplantar and gingival keratoderma · score 0.08
- hereditary palmoplantar keratoderma, Gamborg-Nielsen type · score 0.08
- Ichthyosis-hypotrichosis syndrome · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P1M0-F1 | alphafold | PREDICTED | 90.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P1M0.
Amino-acid sequence (643 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SLC27A4?
The strongest Open Targets associations for SLC27A4 are ichthyosis prematurity syndrome, neurodegenerative disease, genetic disorder, lamellar ichthyosis and autosomal recessive disease.
How long is the SLC27A4 protein?
The Homo sapiens SLC27A4 protein (UniProt Q6P1M0) is 643 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P1M0 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P1M0 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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