Deoxyribonuclease TATDN1 (TATDN1)
Homo sapiens — UniProt Q6P1N9
Data last refreshed: (UniProt release unknown)
Key facts
Deoxyribonuclease TATDN1 (TATDN1) is a protein from Homo sapiens identified by UniProt accession Q6P1N9, 297 residues long. MolForge cross-references it against 0 known binders and 13 disease associations.
- UniProt accession: Q6P1N9; gene symbol TATDN1.
- Organism: Homo sapiens.
- Length: 297 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and mean platelet volume.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Deoxyribonuclease TATDN1 |
|---|---|
| UniProt accession | Q6P1N9 |
| Gene | TATDN1 |
| Organism | Homo sapiens |
| Length | 297 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (13)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.48
- lysosomal storage disease · score 0.19
- mean platelet volume · score 0.16
- peripheral arterial disease · score 0.09
- traffic air pollution measurement · score 0.09
- triple-negative breast cancer · score 0.08
- non-small cell lung carcinoma · score 0.05
- protein measurement · score 0.04
- hepatocellular carcinoma · score 0.03
- preterm premature rupture of the membranes · score 0.03
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P1N9-F1 | alphafold | PREDICTED | 97.98 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P1N9.
Amino-acid sequence (297 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with TATDN1?
The strongest Open Targets associations for TATDN1 are neurodegenerative disease, lysosomal storage disease, mean platelet volume, peripheral arterial disease and traffic air pollution measurement.
How long is the TATDN1 protein?
The Homo sapiens TATDN1 protein (UniProt Q6P1N9) is 297 amino acids long.
Browse: Targets: T · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P1N9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P1N9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.