Enhancer of mRNA-decapping protein 4 (EDC4)
Homo sapiens — UniProt Q6P2E9
Data last refreshed: (UniProt release unknown)
Key facts
Enhancer of mRNA-decapping protein 4 (EDC4) is a protein from Homo sapiens identified by UniProt accession Q6P2E9, 1401 residues long. MolForge cross-references it against 0 known binders and 56 disease associations.
- UniProt accession: Q6P2E9; gene symbol EDC4.
- Organism: Homo sapiens.
- Length: 1401 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, lysosomal storage disease and oral cavity carcinoma.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Enhancer of mRNA-decapping protein 4 |
|---|---|
| UniProt accession | Q6P2E9 |
| Gene | EDC4 |
| Organism | Homo sapiens |
| Length | 1401 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (56)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.54
- lysosomal storage disease · score 0.36
- oral cavity carcinoma · score 0.16
- hepatocellular carcinoma · score 0.06
- high density lipoprotein cholesterol measurement · score 0.05
- primary familial polycythemia due to EPO receptor mutation · score 0.05
- apolipoprotein A 1 measurement · score 0.05
- Pyruvate kinase hyperactivity · score 0.04
- Blackfan-Diamond anemia · score 0.04
- mean corpuscular hemoglobin concentration · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P2E9-F1 | alphafold | PREDICTED | 62.05 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P2E9.
Amino-acid sequence (1401 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with EDC4?
The strongest Open Targets associations for EDC4 are neurodegenerative disease, lysosomal storage disease, oral cavity carcinoma, hepatocellular carcinoma and high density lipoprotein cholesterol measurement.
How long is the EDC4 protein?
The Homo sapiens EDC4 protein (UniProt Q6P2E9) is 1401 amino acids long.
Browse: Targets: E · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P2E9 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P2E9 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.