Centrosomal protein of 85 kDa (CEP85)

Homo sapiens — UniProt Q6P2H3

Gene: CEP85Homo sapiensSwissProt reviewed

About Centrosomal protein of 85 kDa

Centrosomal protein of 85 kDa (CEP85) is a protein from Homo sapiens identified by UniProt accession Q6P2H3, 762 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

Target properties

Protein nameCentrosomal protein of 85 kDa
UniProt accessionQ6P2H3
GeneCEP85
OrganismHomo sapiens
Length762 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (20)

Diseases linked to this target (Open Targets).

  • monocyte count · score 0.09
  • asthma · score 0.08
  • brain measurement · score 0.07
  • granulocyte percentage of myeloid white cells · score 0.07
  • PR interval · score 0.06
  • platelet count · score 0.05
  • lymphocyte count · score 0.05
  • eosinophil percentage of leukocytes · score 0.04
  • platelet crit · score 0.04
  • body height at birth · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6P2H3-F1alphafoldPREDICTED66.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P2H3.

Amino-acid sequence (762 residues)

MAMQEKYPTE GISHVTSPSS DVIQKGSSLG TEWQTPVISE PFRSRFSRCS SVADSGDTAI GTSCSDIAED FCSSSGSPPF QPIKSHVTIP TAHVMPSTLG TSPAKPNSTP VGPSSSKLPL SGLAESVGMT RNGDLGAMKH SPGLSRDLMY FSGATGENGI EQSWFPAVGH ERQEEARKFD IPSMESTLNQ SAMMETLYSD PHHRVRFHNP RTSTSKELYR VLPEAKKAPG SGAVFERNGP HSNSSGVLPL GLQPAPGLSK PLPSQVWQPS PDTWHPREQS CELSTCRQQL ELIRLQMEQM QLQNGAICHH PAAFGPSLPI LEPAQWISIL NSNEHLLKEK ELLIDKQRKH ISQLEQKVRE SELQVHSALL GRPAPFGDVC LLRLQELQRE NTFLRAQFAQ KTEALSREKI DLEKKLSASE VEVQLIRESL KVALQKHSEE VKKQEERVKG RDKHINNLKK KCQKESEQNR EKQQRIETLE RYLADLPTLE DHQKQSQQLK DSELKSTELQ EKVTELESLL EETQAICREK EIQLESLRQR EAEFSSAGHS LQDKQSVEET SGEGPEVEME SWQKRYDSLQ KIVEKQQQKM DQLRSQVQSL EQEVAQEEGT SQALREEAQR RDSALQQLRT AVKELSVQNQ DLIEKNLTLQ EHLRQAQPGS PPSPDTAQLA LELHQELASC LQDLQAVCSI VTQRAQGHDP NLSLLLGIHS AQHPETQLDL QKPDVIKRKL EEVQQLRRDI EDLRTTMSDR YAQDMGENCV TQ

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Quick facts

UniProtQ6P2H3
GeneCEP85
OrganismHomo sapiens
Length762
Binders0
Diseases20
View on UniProt