Oxaloacetate tautomerase FAHD2B, mitochondrial (FAHD2B)
Homo sapiens — UniProt Q6P2I3
Data last refreshed: (UniProt release unknown)
Key facts
Oxaloacetate tautomerase FAHD2B, mitochondrial (FAHD2B) is a protein from Homo sapiens identified by UniProt accession Q6P2I3, 314 residues long. MolForge cross-references it against 0 known binders and 11 disease associations.
- UniProt accession: Q6P2I3; gene symbol FAHD2B.
- Organism: Homo sapiens.
- Length: 314 amino acids.
- Top disease associations (Open Targets): cortical surface area measurement, alcohol consumption measurement and brain measurement.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Oxaloacetate tautomerase FAHD2B, mitochondrial |
|---|---|
| UniProt accession | Q6P2I3 |
| Gene | FAHD2B |
| Organism | Homo sapiens |
| Length | 314 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (11)
Diseases linked to this target (Open Targets).
- cortical surface area measurement · score 0.13
- alcohol consumption measurement · score 0.11
- brain measurement · score 0.11
- bipolar disorder · score 0.08
- schizophrenia · score 0.08
- response to lithium ion · score 0.08
- cortical thickness · score 0.05
- serum non-albumin protein measurement · score 0.03
- acute lymphoblastic leukemia · score 0.00
- unipolar depression · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P2I3-F1 | alphafold | PREDICTED | 93.15 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P2I3.
Amino-acid sequence (314 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with FAHD2B?
The strongest Open Targets associations for FAHD2B are cortical surface area measurement, alcohol consumption measurement, brain measurement, bipolar disorder and schizophrenia.
How long is the FAHD2B protein?
The Homo sapiens FAHD2B protein (UniProt Q6P2I3) is 314 amino acids long.
Browse: Targets: F · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P2I3 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P2I3 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.