NBPF family member NBPF10 (NBPF10)
Homo sapiens — UniProt Q6P3W6
Gene: NBPF10Homo sapiensSwissProt reviewed
Data last refreshed: (UniProt release unknown)
Key facts
NBPF family member NBPF10 (NBPF10) is a protein from Homo sapiens identified by UniProt accession Q6P3W6, 3795 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.
- UniProt accession: Q6P3W6; gene symbol NBPF10.
- Organism: Homo sapiens.
- Length: 3795 amino acids.
- Top disease associations (Open Targets): serum albumin measurement, hepatocellular carcinoma and neoplasm.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | NBPF family member NBPF10 |
|---|---|
| UniProt accession | Q6P3W6 |
| Gene | NBPF10 |
| Organism | Homo sapiens |
| Length | 3795 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (28)
Diseases linked to this target (Open Targets).
- serum albumin measurement · score 0.04
- hepatocellular carcinoma · score 0.02
- neoplasm · score 0.01
- cancer · score 0.01
- gonorrhea · score 0.01
- Huntington disease · score 0.01
- glioblastoma multiforme · score 0.00
- Kidney Oncocytoma · score 0.00
- lung adenocarcinoma · score 0.00
- prostatitis · score 0.00
3D Structure (10)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P3W6-F1 | alphafold | PREDICTED | 42.69 | — |
| AF-Q6P3W6-F2 | alphafold | PREDICTED | 38.87 | — |
| AF-Q6P3W6-F6 | alphafold | PREDICTED | 36.74 | — |
| AF-Q6P3W6-F8 | alphafold | PREDICTED | 36.18 | — |
| AF-Q6P3W6-F13 | alphafold | PREDICTED | 36.17 | — |
| AF-Q6P3W6-F7 | alphafold | PREDICTED | 36.13 | — |
| AF-Q6P3W6-F12 | alphafold | PREDICTED | 36.11 | — |
| AF-Q6P3W6-F9 | alphafold | PREDICTED | 35.83 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P3W6.
Amino-acid sequence (3795 residues)
MVVSAGPWSS EKAEMNILEI NETLRPQLAE KKQQFRSLKE KCFLTQLAGF LANRQKKYKY EECKDLIKFM LRNERQFKEE KLAEQLKQAE ELRQYKVLVH SQERELTQLR EKLREGRDAS RSLYEHLQAL LTPDEPDKSQ GQDLQEQLAE GCRLAQHLVQ KLSPENDEDE DEDVQVEEAE KVLESSAPRE VQKAEESKVP EDSLEECAIT CSNSHGPCDS NQPHKNIKIT FEEDEVNSTL VVDRESSHDE CQDALNILPV PGPTSSATNV SMVVSAGPLS SEKAEMNILE INEKLRPQLA EKKQQFRNLK EKCFLTQLSG FLANQQKKYK YEECKDLIKF MLRNERQFKE EKLAEQLKQA EELRQYKVLV HAQERELTQL KEKLREGRDA SRSLNEHLQA LLTPYEPDKS QGQDLQEQLA EGCRLAQHLV QKLSPENDND DDEDVQVEVA EKVQKSSAPR EMQKAEEKEV PEDSLEECAI TYSNSHGSYD SNQPHRKTKI TFEEDKVDST LIGSSSHVEW EDAVHIIPEN ESDDEEEEEK GPVSPRNLQE SEEEEVPQES WDEGYSTLSI PPEMLASYQS YSSTFHSLEE QQVCMAVDIG RHRWDQVKKE DQEATGPRLS RELLDEKGPE VLQDSQDRCY STPSGCLELT DSCQPYRSAF YILEQQRVGL AIDMDEIEKY QEVEEDQDPS CPRLSRELLD EKEPEVLQDS LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD RIKKDQEEEE DQGPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF SLDVGEIEKK GKGKKRRGRR SKKERRRGRK EGEEDQNPPC PRLSRELLDE KGPEVLQDSL DRCYSTPSGC LELTDSCQPY RSAFYVLEQQ RVGFAFDMDE IEKYQEVEED QDPSCPRLSR ELLDEKEPEV LQDSLDRCYS TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRIKKDE EEEEDQDPPC PRLSRELLEV VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY GSSFYALEEN HVGFSLDVGE IEKKGKGKKR RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE LLEEKGPEVL QDSLDRCYST PSGCLELTDS CQPYRSAFYV LEQQRVGFAV DMDEIEKYQE VEEDQDPSCP RLSRELLDEK EPEVLQDSLD RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY LGLALDVDRI KKDEEEEEDQ DPPCPRLSRE LLEVVEPEVL QDSLDRCYST PSSCLEQPDS CQPYGSSFYA LEEKHVGFSL DVGEIEKKGK GKKRRGRRSK KERRRGRKEG EEDQNPPCPR LSRELLEEKG PEVLQDSLDR CYSTPSGCLE LTDSCQPYRS AFYVLEQQRV GFAVDMDEIE KYQEVEEDQD PSCPRLSREL LDEKEPEVLQ DSLDRCYSTP SGYLELPDLG QPYSSAVYSL EEQYLGLALD VDRIKKDEEE EEDQDPPCPR LSRELLEVVE PEVLQDSLDR CYSTPSSCLE QPDSCQPYGS SFYALEEKHV GFSLDVGEIE KKGKGKKRRG RRSKKERRRG RKEGEEDQNP PCPRLSRELL DEKGPEVLQD SLDRCYSTPS GCLELTDSCQ PYRSAFYVLE QQHVGLAVDM DEIEKYQEVE EDQDPSCPRL SRELLDEKEP EVLQDSLDRC YSTPSGYLEL PDLGQPYSSA VYSLEEQYLG LALDVDRIKK DQEEEEDQGP PCPRLSRELL EVVEPEVLQD SLDRCYSTPS SCLEQPDSCQ PYGSSFYALE EKHVGFSLDV GEIEKKGKGK KRRGRRSKKE RRRGRKEGEE DQNPPCPRLS RELLDEKGPE VLQDSLDRCY STPSGCLELT DSCQPYRSAF YVLEQQHVGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLD EKEPEVLQDS LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD RIKKDQEEEE DQGPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF SLDVGEIEKK GKGKKRRGRR SKKERRRGRK EGEEDQNPPC PRLSRELLDE KGPEVLQDSL DRCYSTPSGC LELTDSCQPY RSAFYVLEQQ HVGLAVDMDE IEKYQEVEED QDPSCPRLSR ELLDEKEPEV LQDSLDRCYS TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRIKKDQ EEEEDQGPPC PRLSRELLEV VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY GSSFYALEEK HVGFSLDVGE IEKKGKGKKR RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE LLDEKGPEVL QDSLDRCYST PSGCLELTDS CQPYRSAFYV LEQQHVGLAV DMDEIEKYQE VEEDQDPSCP RLSRELLDEK EPEVLQDSLD RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY LGLALDVDRI KKDQEEEEDQ DPPCPRLSRE LLEVVEPEVL QDSLDRCYST PSSCLEQPDS CQPYGSSFYA LEEKHVGFSL DVGEIEKKGK GKKRRGRRSK KERRRGRKEG EEDQNPPCPR LSRELLDEKG PEVLQDSLDR CYSTPSGCLE LTDSCQPYRS AFYVLEQQHV GLAVDMDEIE KYQEVEEDQD PSCPRLSREL LDEKEPEVLQ DSLDRCYSTP SGYLELPDLG QPYSSAVYSL EEQYLGLALD VDRIKKDQEE EEDQGPPCPR LSRELLEVVE PEVLQDSLDR CYSTPSSCLE QPDSCQPYGS SFYALEEKHV GFSLDVGEIE KKGKGKKRRG RRSKKERRRG RKEGEEDQNP PCPRLSRELL DEKGPEVLQD SLDRCYSTPS GCLELTDSCQ PYRSAFYVLE QQHVGLAVDM DEIEKYQEVE EDQDPSCPRL SRELLDEKEP EVLQDSLDRC YSTPSGYLEL PDLGQPYSSA VYSLEEQYLG LALDVDRIKK DQEEEEDQGP PCPRLSRELL EVVEPEVLQD SLDRCYSTPS SCLEQPDSCQ PYGSSFYALE EKHVGFSLDV GEIEKKGKGK KRRGRRSKKE RRRGRKEGEE DQNPPCPRLS RELLDEKGPE VLQDSLDRCY STPSGCLELT DSCQPYRSAF YVLEQQHVGL AVDMDEIEKY QEVEEDQDPS CPRLSRELLD EKEPEVLQDS LDRCYSTPSG YLELPDLGQP YSSAVYSLEE QYLGLALDVD RIKKDEEEEE DQDPPCPRLS RELLEVVEPE VLQDSLDRCY STPSSCLEQP DSCQPYGSSF YALEEKHVGF SLDVGEIEKK GKGKKRRGRR SKKERRRGRK EGEEDQNPPC PRLSRELLDE KGPEVLQDSL DRCYSTPSGY LELTDSCQPY RSAFYVLEQQ HVGLAVDMDE IEKYQEVEED QDPSCPRLSR ELLDEKEPEV LQDSLDRCYS TPSGYLELPD LGQPYSSAVY SLEEQYLGLA LDVDRIKKDQ EEEEDQGPPC PRLSRELLEV VEPEVLQDSL DRCYSTPSSC LEQPDSCQPY GSSFYALEEK HVGFSLDVGE IEKKGKGKKR RGRRSKKERR RGRKEGEEDQ NPPCPRLSRE LLDEKGPEVL QDSLDRCYST PSGCLELCDS CQPYRSAFYV LEQQRVGLAV DMDEIEKYQE VEEDQDPSCP RLSRELLDEK EPEVLQDSLD RCYSTPSGYL ELPDLGQPYS SAVYSLEEQY LGLALDVDKI EKKGKGKKRR GRRSKKERRR GRKEGEEDQN PPCPRLNGVL MEVEEREVLQ DSLDRCYSTP SMYFELPDSF QHYRSVFYSF EEQHISFALY VDNRFFTLTV TSLHLVFQMG VIFPQ
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with NBPF10?
The strongest Open Targets associations for NBPF10 are serum albumin measurement, hepatocellular carcinoma, neoplasm, cancer and gonorrhea.
How long is the NBPF10 protein?
The Homo sapiens NBPF10 protein (UniProt Q6P3W6) is 3795 amino acids long.
Browse: Targets: N · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P3W6 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P3W6 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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