SCY1-like protein 2 (SCYL2)
Homo sapiens — UniProt Q6P3W7
Data last refreshed: (UniProt release unknown)
Key facts
SCY1-like protein 2 (SCYL2) is a protein from Homo sapiens identified by UniProt accession Q6P3W7, 929 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.
- UniProt accession: Q6P3W7; gene symbol SCYL2.
- Organism: Homo sapiens.
- Length: 929 amino acids.
- Top disease associations (Open Targets): arthrogryposis multiplex congenita 4, neurogenic, with agenesis of the corpus callosum, genetic disorder and heel bone mineral density.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | SCY1-like protein 2 |
|---|---|
| UniProt accession | Q6P3W7 |
| Gene | SCYL2 |
| Organism | Homo sapiens |
| Length | 929 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (14)
Diseases linked to this target (Open Targets).
- arthrogryposis multiplex congenita 4, neurogenic, with agenesis of the corpus callosum · score 0.61
- genetic disorder · score 0.41
- heel bone mineral density · score 0.38
- Neurogenic arthrogryposis multiplex congenita · score 0.37
- total cholesterol measurement · score 0.30
- neurodegenerative disease · score 0.29
- urate measurement · score 0.29
- bone density · score 0.29
- adolescent idiopathic scoliosis · score 0.02
- psoriasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P3W7-F1 | alphafold | PREDICTED | 70.76 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P3W7.
Amino-acid sequence (929 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with SCYL2?
The strongest Open Targets associations for SCYL2 are arthrogryposis multiplex congenita 4, neurogenic, with agenesis of the corpus callosum, genetic disorder, heel bone mineral density, Neurogenic arthrogryposis multiplex congenita and total cholesterol measurement.
How long is the SCYL2 protein?
The Homo sapiens SCYL2 protein (UniProt Q6P3W7) is 929 amino acids long.
Browse: Targets: S · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P3W7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P3W7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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