PiggyBac transposable element-derived protein 2 (PGBD2)
Homo sapiens — UniProt Q6P3X8
Data last refreshed: (UniProt release unknown)
Key facts
PiggyBac transposable element-derived protein 2 (PGBD2) is a protein from Homo sapiens identified by UniProt accession Q6P3X8, 592 residues long. MolForge cross-references it against 0 known binders and 18 disease associations.
- UniProt accession: Q6P3X8; gene symbol PGBD2.
- Organism: Homo sapiens.
- Length: 592 amino acids.
- Top disease associations (Open Targets): mean corpuscular volume, platelet count and platelet crit.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | PiggyBac transposable element-derived protein 2 |
|---|---|
| UniProt accession | Q6P3X8 |
| Gene | PGBD2 |
| Organism | Homo sapiens |
| Length | 592 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (18)
Diseases linked to this target (Open Targets).
- mean corpuscular volume · score 0.31
- platelet count · score 0.29
- platelet crit · score 0.28
- erythrocyte count · score 0.24
- red blood cell density measurement · score 0.19
- monocyte count · score 0.15
- hypertension · score 0.12
- lymphocyte count · score 0.10
- uterine fibroid · score 0.08
- systolic blood pressure · score 0.08
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P3X8-F1 | alphafold | PREDICTED | 82.95 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P3X8.
Amino-acid sequence (592 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with PGBD2?
The strongest Open Targets associations for PGBD2 are mean corpuscular volume, platelet count, platelet crit, erythrocyte count and red blood cell density measurement.
How long is the PGBD2 protein?
The Homo sapiens PGBD2 protein (UniProt Q6P3X8) is 592 amino acids long.
Browse: Targets: P · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P3X8 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P3X8 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
How this page is built: methodology · editorial policy & corrections.
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