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Protein GOLM2 (GOLM2)

Homo sapiens — UniProt Q6P4E1

Gene: GOLM2Homo sapiensSwissProt reviewed

Data last refreshed: (UniProt release unknown)

Key facts

Protein GOLM2 (GOLM2) is a protein from Homo sapiens identified by UniProt accession Q6P4E1, 436 residues long. MolForge cross-references it against 0 known binders and 20 disease associations.

  • UniProt accession: Q6P4E1; gene symbol GOLM2.
  • Organism: Homo sapiens.
  • Length: 436 amino acids.
  • Top disease associations (Open Targets): lean body mass, fat body mass and whole body water mass.
  • 3D structure: AlphaFold model available.

Target properties

Protein nameProtein GOLM2
UniProt accessionQ6P4E1
GeneGOLM2
OrganismHomo sapiens
Length436 residues
Molecular weight—
EC numbers—
Target class—
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (20)

Diseases linked to this target (Open Targets).

  • lean body mass · score 0.11
  • fat body mass · score 0.10
  • whole body water mass · score 0.10
  • base metabolic rate measurement · score 0.09
  • electrocardiography · score 0.09
  • triglyceride measurement · score 0.09
  • high density lipoprotein cholesterol measurement · score 0.09
  • alcohol drinking · score 0.08
  • alcohol consumption measurement · score 0.08
  • platelet count · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q6P4E1-F1alphafoldPREDICTED65.92—

Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P4E1.

Amino-acid sequence (436 residues)

MVGFGANRRA GRLPSLVLVV LLVVIVVLAF NYWSISSRHV LLQEEVAELQ GQVQRTEVAR GRLEKRNSDL LLLVDTHKKQ IDQKEADYGR LSSRLQAREG LGKRCEDDKV KLQNNISYQM ADIHHLKEQL AELRQEFLRQ EDQLQDYRKN NTYLVKRLEY ESFQCGQQMK ELRAQHEENI KKLADQFLEE QKQETQKIQS NDGKELDINN QVVPKNIPKV AENVADKNEE PSSNHIPHGK EQIKRGGDAG MPGIEENDLA KVDDLPPALR KPPISVSQHE SHQAISHLPT GQPLSPNMPP DSHINHNGNP GTSKQNPSSP LQRLIPGSNL DSEPRIQTDI LKQATKDRVS DFHKLKQSRF FDENESPVDP QHGSKLADYN GDDGNVGEYE ADKQAELAYN EEEDGDGGEE DVQDDEEREL QMDPADYGKQ HFNDVL

Frequently asked questions

Answers are generated from the structured data on this page, not written by hand.

Which diseases are associated with GOLM2?

The strongest Open Targets associations for GOLM2 are lean body mass, fat body mass, whole body water mass, base metabolic rate measurement and electrocardiography.

How long is the GOLM2 protein?

The Homo sapiens GOLM2 protein (UniProt Q6P4E1) is 436 amino acids long.

Browse: Targets: G · all protein targets A–Z · drugs A–Z.

Sources

How this page is built: methodology · editorial policy & corrections.

For research and educational use only — not medical advice. This page is compiled automatically from public databases. It is not written or reviewed by a clinician. Do not start, stop or change any treatment based on it; consult a qualified healthcare professional. Spotted an error? See our corrections policy or email hello@molforge.ai.

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Quick facts

UniProtQ6P4E1
GeneGOLM2
OrganismHomo sapiens
Length436
Binders0
Diseases20
View on UniProt