Metal transporter CNNM4 (CNNM4)
Homo sapiens — UniProt Q6P4Q7
Data last refreshed: (UniProt release unknown)
Key facts
Metal transporter CNNM4 (CNNM4) is a protein from Homo sapiens identified by UniProt accession Q6P4Q7, 775 residues long. MolForge cross-references it against 0 known binders and 129 disease associations.
- UniProt accession: Q6P4Q7; gene symbol CNNM4.
- Organism: Homo sapiens.
- Length: 775 amino acids.
- Target class: Transporter.
- Top disease associations (Open Targets): Jalili syndrome, calcium measurement and Retinal dystrophy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Metal transporter CNNM4 |
|---|---|
| UniProt accession | Q6P4Q7 |
| Gene | CNNM4 |
| Organism | Homo sapiens |
| Length | 775 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | Transporter (inferred from UniProt keywords / EC) |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (129)
Diseases linked to this target (Open Targets).
- Jalili syndrome · score 0.77
- calcium measurement · score 0.48
- Retinal dystrophy · score 0.41
- diastolic blood pressure · score 0.31
- bipolar disorder · score 0.30
- smoking status measurement · score 0.29
- schizophrenia · score 0.28
- blood phosphate measurement · score 0.26
- alcohol drinking · score 0.26
- unipolar depression · score 0.25
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P4Q7-F1 | alphafold | PREDICTED | 76.54 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P4Q7.
Amino-acid sequence (775 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with CNNM4?
The strongest Open Targets associations for CNNM4 are Jalili syndrome, calcium measurement, Retinal dystrophy, diastolic blood pressure and bipolar disorder.
How long is the CNNM4 protein?
The Homo sapiens CNNM4 protein (UniProt Q6P4Q7) is 775 amino acids long.
Browse: Targets: C · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P4Q7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P4Q7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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