Glutathione hydrolase 6 (GGT6)
Homo sapiens — UniProt Q6P531
Data last refreshed: (UniProt release unknown)
Key facts
Glutathione hydrolase 6 (GGT6) is a protein from Homo sapiens identified by UniProt accession Q6P531, 493 residues long. MolForge cross-references it against 0 known binders and 27 disease associations.
- UniProt accession: Q6P531; gene symbol GGT6.
- Organism: Homo sapiens.
- Length: 493 amino acids.
- Top disease associations (Open Targets): leukocyte count, clear cell renal carcinoma and rheumatic disease.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Glutathione hydrolase 6 |
|---|---|
| UniProt accession | Q6P531 |
| Gene | GGT6 |
| Organism | Homo sapiens |
| Length | 493 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (27)
Diseases linked to this target (Open Targets).
- leukocyte count · score 0.05
- clear cell renal carcinoma · score 0.04
- rheumatic disease · score 0.03
- hepatocellular carcinoma · score 0.03
- papillary renal cell carcinoma · score 0.02
- prostate carcinoma · score 0.02
- esophageal squamous cell carcinoma · score 0.02
- oral squamous cell carcinoma · score 0.02
- neoplasm · score 0.02
- chronic interstitial cystitis · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P531-F1 | alphafold | PREDICTED | 71.23 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P531.
Amino-acid sequence (493 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with GGT6?
The strongest Open Targets associations for GGT6 are leukocyte count, clear cell renal carcinoma, rheumatic disease, hepatocellular carcinoma and papillary renal cell carcinoma.
How long is the GGT6 protein?
The Homo sapiens GGT6 protein (UniProt Q6P531) is 493 amino acids long.
Browse: Targets: G · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P531 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P531 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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