Leiomodin-2 (LMOD2)
Homo sapiens — UniProt Q6P5Q4
Data last refreshed: (UniProt release unknown)
Key facts
Leiomodin-2 (LMOD2) is a protein from Homo sapiens identified by UniProt accession Q6P5Q4, 547 residues long. MolForge cross-references it against 0 known binders and 207 disease associations.
- UniProt accession: Q6P5Q4; gene symbol LMOD2.
- Organism: Homo sapiens.
- Length: 547 amino acids.
- Top disease associations (Open Targets): cardiomyopathy, dilated, 2G, familial isolated dilated cardiomyopathy and dilated cardiomyopathy.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Leiomodin-2 |
|---|---|
| UniProt accession | Q6P5Q4 |
| Gene | LMOD2 |
| Organism | Homo sapiens |
| Length | 547 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (207)
Diseases linked to this target (Open Targets).
- cardiomyopathy, dilated, 2G · score 0.60
- familial isolated dilated cardiomyopathy · score 0.46
- dilated cardiomyopathy · score 0.38
- Dilated cardiomyopathy · score 0.38
- platelet count · score 0.33
- reticulocyte count · score 0.33
- HbA1c measurement · score 0.32
- mean platelet volume · score 0.30
- genetic disorder · score 0.19
- mean corpuscular hemoglobin concentration · score 0.18
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P5Q4-F1 | alphafold | PREDICTED | 66.93 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P5Q4.
Amino-acid sequence (547 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with LMOD2?
The strongest Open Targets associations for LMOD2 are cardiomyopathy, dilated, 2G, familial isolated dilated cardiomyopathy, dilated cardiomyopathy, Dilated cardiomyopathy and platelet count.
How long is the LMOD2 protein?
The Homo sapiens LMOD2 protein (UniProt Q6P5Q4) is 547 amino acids long.
Browse: Targets: L · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P5Q4 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P5Q4 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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