Ribonuclease kappa (RNASEK)
Homo sapiens — UniProt Q6P5S7
Data last refreshed: (UniProt release unknown)
Key facts
Ribonuclease kappa (RNASEK) is a protein from Homo sapiens identified by UniProt accession Q6P5S7, 137 residues long. MolForge cross-references it against 0 known binders and 30 disease associations.
- UniProt accession: Q6P5S7; gene symbol RNASEK.
- Organism: Homo sapiens.
- Length: 137 amino acids.
- Top disease associations (Open Targets): neurodegenerative disease, serum metabolite measurement and lymphocyte percentage of leukocytes.
- 3D structure: AlphaFold model available.
Target properties
| Protein name | Ribonuclease kappa |
|---|---|
| UniProt accession | Q6P5S7 |
| Gene | RNASEK |
| Organism | Homo sapiens |
| Length | 137 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | — |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|---|
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.53
- serum metabolite measurement · score 0.11
- lymphocyte percentage of leukocytes · score 0.10
- drug use measurement · score 0.10
- neutrophil percentage of leukocytes · score 0.08
- isolated asymptomatic elevation of creatine phosphokinase · score 0.07
- blood metabolite measurement · score 0.07
- lymphocyte count · score 0.07
- mean platelet volume · score 0.06
- total blood protein measurement · score 0.05
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|---|---|---|---|
| AF-Q6P5S7-F1 | alphafold | PREDICTED | 66.39 | — |
Experimental structures are not indexed in MolForge yet — search RCSB PDB for Q6P5S7.
Amino-acid sequence (137 residues)
Frequently asked questions
Answers are generated from the structured data on this page, not written by hand.
Which diseases are associated with RNASEK?
The strongest Open Targets associations for RNASEK are neurodegenerative disease, serum metabolite measurement, lymphocyte percentage of leukocytes, drug use measurement and neutrophil percentage of leukocytes.
How long is the RNASEK protein?
The Homo sapiens RNASEK protein (UniProt Q6P5S7) is 137 amino acids long.
Browse: Targets: R · all protein targets A–Z · drugs A–Z.
Sources
- UniProtKB Q6P5S7 — name, gene, function, sequence, keywords (CC BY 4.0)
- AlphaFold DB Q6P5S7 — predicted 3D structure (CC BY 4.0)
- Open Targets Platform — disease associations and tractability (CC0)
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